Study of the correlation between growth hormone deficiency and serum leptin, adiponectin, and visfatin levels in adults.

@article{Li2014StudyOT,
  title={Study of the correlation between growth hormone deficiency and serum leptin, adiponectin, and visfatin levels in adults.},
  author={Z-P Li and M. Zhang and Jiali Gao and Gy Zhou and S-Q Li and Zhenmei An},
  journal={Genetics and molecular research : GMR},
  year={2014},
  volume={13 2},
  pages={
          4050-6
        }
}
  • Z-P Li, M. Zhang, +3 authors Z. An
  • Published 14 February 2014
  • Biology, Medicine
  • Genetics and molecular research : GMR
We aimed to determine the significance and changes in leptin, adiponectin (ADP), and visfatin levels in adults with growth hormone deficiency (GHD). Forty adults (19 men, 21 women) who had been diagnosed with GHD comprised the observation group, while 36 healthy adults (18 men, 18 women) were used as the control group. Fasting venous blood was collected to detect leptin, ADP, and visfatin levels. There was no statistically significant difference (P > 0.05) between the GHD group and the control… 
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Highly Influential Citations
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10 Citations

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Citation Type

Resistin, visfatin, leptin and omentin are differently related to hormonal and metabolic parameters in growth hormone-deficient children
TLDR
GH treatment modifies adipokine secretion and the perturbation of some adipokines levels could contribute to the clinical and metabolic changes observed during the follow-up.
The correlation between insulin-like growth factor 1 (IGF-1) and novel adipocytokines in postmenopausal women: A population-based study
TLDR
There is a significant correlation between serum IGF-1 and visfatin levels in postmenopausal women beyond metabolic syndrome, type 2 diabetes, bone formation markers, and hs-CRP levels, and the observed correlation might be a physiological compensation and adaptation to protect against visFatin-induced proinflammatory effects.
Serum Lipid and Leptin Concentrations in Patients with Sheehan Syndrome
TLDR
It is demonstrated that patients with SS have an abnormal lipid profile, and raised leptin levels as compared to age and BMI matched controls.
Reduced peak stimulated growth hormone is associated with hyperuricemia in obese children and adolescents
TLDR
Data indicate that lower peak GH is positively associated with hyperuricemia in obese children and adolescents without known hypothalamic/pituitary disease after controlling BMI and insulin resistance, as well as other cardiometabolic risk factors.
A new clinical test to diagnose growth hormone deficiency in saliva of patients with short stature
Growth hormone deficiency (GHD) is one of the most common endocrine disorders with short stature in children. This study aims to suggest a novel test to assess the level of IGFBP-3 in saliva as a new…
Relationship of fibroblast growth factor 21, sirtuin 1, visfatin, and regulators in children with short stature
TLDR
The decrease in visfatin value in the short-stature group is thought to be due to an insufficient amount of adipose tissue, which is important for growth and development, and the result of this reduction of SIRT1 would negatively impact IGF-1 and IGFBP-3 production.
Bone health and body composition of children and adolescents with growth hormone deficiency
TLDR
The findings indicate that adolescents with CO-GHD have a low bone mass, despite prior long term rhGH replacement therapy, and suggest that muscle force and serum PTH may be important determinants of bone health in subjects with CO -GHD.
A Functional Interplay between IGF-1 and Adiponectin
TLDR
The IGF-1 and adiponectin systems are described briefly, and their putative interplay in relation to several pathological conditions, including obesity, diabetes, insulin resistance, cardiovascular disease, and cancer are focused on.
The role of leptin in regulating bone metabolism.
Management of Adult Growth Hormone Deficiency at Peking Union Medical College Hospital: A Survey among Physicians.

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