Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia.

@article{Bzard2013StudyOT,
  title={Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia.},
  author={Erwan B{\'e}zard and Elisabetta Tronci and Elsa Y. Pioli and Qin Li and Gr{\'e}gory Porras and Anders Bj{\"o}rklund and Manolo Carta},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2013},
  volume={28 8},
  pages={1088-96}
}
The serotonin (5-hydroxytryptamine [5HT]) system has recently emerged as an important player in the appearance of l-3,4-dihydroxyphenylalanine (levodopa [l-dopa])-induced dyskinesia in animal models of Parkinson's disease. In fact, dopamine released as a false transmitter from serotonin neurons appears to contribute to the pulsatile stimulation of dopamine receptors, leading to the appearance of the abnormal involuntary movements. Thus, drugs able to dampen the activity of serotonin neurons… CONTINUE READING
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