• Corpus ID: 212496479

Study of the Possible Modulatory Effect of Resveratrol and Coenzyme Q10 on MPTP-Induced Parkinsonism in Mice

  title={Study of the Possible Modulatory Effect of Resveratrol and Coenzyme Q10 on MPTP-Induced Parkinsonism in Mice},
  author={Mohamed Abdel Rahman and Ayman Elsheikh},
Background: Parkinson's disease is a motor system disease caused by factors that compromise survival of the dopaminergic neurons in the substantia nigra. The mechanisms of degeneration of these neurons include mitochondrial dysfunction, oxidative stress and neuroinflammation. CoQ10 is a fat-soluble vitamin found in the inner mitochondrial membrane and is involved in the electron transport chain that supplies energy to vital organs. Resveratrol is a natural polyphenolic compound found in grapes… 


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