Study of the Association of CYP 2 D 6 * 4 Polymorphism with the Susceptibility of HCV-Related Liver Cirrhosis and Liver Cancer

Abstract

Background: CYP2D6 is a member of cytochrome P450 enzymes family which is involved in detoxification of a wide range of xenobiotics and drugs. Several genetic polymorphisms had been shown to affect its activity which may results in increased susceptibility to malignant disorders. Aim: to detect if there is specific cytochrome CYP2D6*4 genotype associated… (More)

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