Study of the γD-crystallin protein using two-dimensional infrared (2DIR) spectroscopy: experiment and simulation.

@article{Lam2013StudyOT,
  title={Study of the γD-crystallin protein using two-dimensional infrared (2DIR) spectroscopy: experiment and simulation.},
  author={Alfonso Lam and Sean D. Moran and Nicholas K. Preketes and Tianqi O. Zhang and Martin T Zanni and Shaul Mukamel},
  journal={The journal of physical chemistry. B},
  year={2013},
  volume={117 49},
  pages={15436-43}
}
Cataracts is a misfolding protein disease in which one of the major components is the γD-crystallin protein. The conformational structure of the aggregated γD-crystallin and the interactions that cause aggregation are largely unknown. A recent experimental two-dimensional infrared (2DIR) spectroscopy study determined that the C-terminal domain has a high… CONTINUE READING