Algal techniques were used to study the soil factors affecting the toxicity of herbicides. It was found that the organic matter adsorbed 18 times more herbicide than clay. The inherent phytotoxicity of different herbicides was tested by these methods and the results obtained compared favourably to those of higher plants. The order of toxicity as tested by algae was: diuron >neburon>monuron>atrazine>simazine>atratone. The prediction of application rates of diuron and simazine by algal methods was tested in the field with wheat as cereal crop. The data obtained testified that the predictions were correct and better than the commercial recommendation. Good chemical control of weeds was achieved by herbicide at the early stage of crop growth. At later stages of crop development the toxicity of the chemical was reduced to insignificance and the crop plants were then capable to compete successfully against the emerging weeds. Thus a biological weed control was obtained. Such combined chemical-biological weed control technique should be regarded as the most desirable practice in agriculture.