Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route.

@article{Aune2012StudyOP,
  title={Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route.},
  author={Tore Aune and Arild Espenes and John A Bun{\ae}s Aasen and Michael A. Quilliam and Philipp Hess and Stig Lars{\'e}n},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2012},
  volume={60 5},
  pages={
          895-906
        }
}
Toxins from the okadaic acid (OA) and azaspiracid (AZA) group cause considerable negative health effects in consumers when present in shellfish above certain levels. The main symptoms, dominated by diarrhoea, are caused by damage to the gastrointestinal (GI) tract. Even though OA and AZAs exert toxicity via different mechanisms, it is important to find out whether they may enhance the health effects if present together since they act on the same organs and are regulated individually. In this… CONTINUE READING

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