Study of free oligosaccharides derived from the bacterial N-glycosylation pathway.

  title={Study of free oligosaccharides derived from the bacterial N-glycosylation pathway.},
  author={Harald Nothaft and Xin Liu and David J. McNally and Jianjun Li and Christine M. Szymanski},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={106 35},
The food-borne pathogen Campylobacter jejuni is one of the leading causes of bacterial gastroenteritis worldwide and the most frequent antecedent in neuropathies such as the Guillain-Barré and Miller Fisher syndromes. C. jejuni was demonstrated to possess an N-linked protein glycosylation pathway that adds a conserved heptasaccharide to >40 periplasmic and membrane proteins. Recently, we showed that C. jejuni also produces free heptasaccharides derived from the N-glycan pathway reminiscent of… CONTINUE READING
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