Study of formulation variables on properties of drug-gellan beads by factorial design.

@article{Patil2006StudyOF,
  title={Study of formulation variables on properties of drug-gellan beads by factorial design.},
  author={Sachin Patil and Sameer Sharma and Anagha Nimbalkar and A Krishnamanjari Pawar},
  journal={Drug development and industrial pharmacy},
  year={2006},
  volume={32 3},
  pages={315-26}
}
The aim of the present study was to obtain cross-linked calcium-gellan beads containing diclofenac sodium as model drug, using full 3(3) factorial design. Drug quantity, pH of cross-linking solution, and speed of agitation were selected as variables for factorial design. The resultant beads were evaluated by scanning electron microscopy (SEM), percent yield… CONTINUE READING