Study of flavonoids/beta-cyclodextrins inclusion complexes by NMR, FT-IR, DSC, X-ray investigation.

@article{Ficarra2002StudyOF,
  title={Study of flavonoids/beta-cyclodextrins inclusion complexes by NMR, FT-IR, DSC, X-ray investigation.},
  author={Rita Ficarra and Silvana Tommasini and Daniela Raneri and Maria Luisa Calabr{\'o} and M R Di Bella and Cecilia Rustichelli and Maria Cristina Gamberini and Paola Ficarra},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2002},
  volume={29 6},
  pages={1005-14}
}
Flavonoids are natural substances with a lot of biological activities, including the antioxidant one. Their use in pharmaceutical field is, however, limited by their aqueous insolubility. As the formation of the inclusion complexes can improve their solubility in water, the flavonoids hesperetin, hesperidin, naringenin and naringin have been complexed with beta-cyclodextrin (beta-CD) by the coprecipitation method and studied in solution and in solid state by NMR, FT-IR, differential scanning… CONTINUE READING
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