Study of cell kinetics in anaplastic thyroid carcinoma transplanted to nude mice.

@article{Yoshida1989StudyOC,
  title={Study of cell kinetics in anaplastic thyroid carcinoma transplanted to nude mice.},
  author={Akira Yoshida and Masakatsu Fukazawa and Hiroko Ushio and Yuji Aiyoshi and Shugo Soeda and Katsuki Ito},
  journal={Journal of surgical oncology},
  year={1989},
  volume={41 1},
  pages={1-4}
}
The cell kinetics of the transplantable human anaplastic thyroid carcinoma were studied in athymic nude mice using bromodeoxyuridine (BrdU) pulse labeling. In order to estimate the cell cycle time in this study, the percent labeled mitosis curve was prepared with immunoperoxidase staining using monoclonal antibody to BrdU instead of 3[H]thymidine autoradiography. This technique was considered to be very useful because it can be done for a short term and can still be changed to the… CONTINUE READING