Study of blood metabolism and urinary excretion of chymopapain following intradiscal injection using a high-sensitivity enzyme immunoassay.

@article{Kawano2005StudyOB,
  title={Study of blood metabolism and urinary excretion of chymopapain following intradiscal injection using a high-sensitivity enzyme immunoassay.},
  author={Keiichiro Kawano and Naoya Tajima and Seiichi Hashida and Eiji Ishikawa},
  journal={Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association},
  year={2005},
  volume={10 2},
  pages={206-13}
}
To develop chymopapain-induced chemonucleolysis as an established treatment, it is necessary to determine the kinetics of chymopapain in blood and urine following intradiscal injection. To investigate the rate of blood metabolism and urinary excretion of chymopapain following intradiscal injection, we developed a high-sensitivity enzyme immunoassay for… CONTINUE READING