Study of anaesthetic agents for their ability to elicit porphyrin biosynthesis in chick embryo liver.

Abstract

Effects of some anaesthetic drugs on the activity of delta-aminolevulinate synthetase and on the formation of porphyrins and cytochrome P-450 were studied in 18-day-old chick embryo livers in ovo. The drugs were either tested alone or with a small dose of 1,4-dihydro-3,5-dicarbethoxycollidine, which reproduces in the embryo liver a partial block in the heme… (More)

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@article{Verneuil1983StudyOA, title={Study of anaesthetic agents for their ability to elicit porphyrin biosynthesis in chick embryo liver.}, author={Hubert de Verneuil and Jean Charles Deybach and Nghi Phung and Vin{\'i}cius Duval da Silva and Yves Nordmann}, journal={Biochemical pharmacology}, year={1983}, volume={32 6}, pages={1011-8} }