Study of Ligament Ossification and Abnormal Glucose Tolerance in the Zucker Fatty Rat

@inproceedings{Yamamoto2006StudyOL,
  title={Study of Ligament Ossification and Abnormal Glucose Tolerance in the Zucker Fatty Rat},
  author={Kengo Yamamoto and Kosuke Kubo},
  year={2006}
}
  • Kengo Yamamoto, Kosuke Kubo
  • Published 2006
  • Medicine
  • Significant expression of insulin-sensitive cells and the IGF-I-binding protein CTGF was observed in the cellular hyperplasia areas of the spinal ligament sites and Achilles tendon ectopic ossifi cation sites of Zucker fatty rats. We prepared MSG-treated rats, which exhibit hyperleptinemia and hyperinsulinemia from 6 months of age onward, as in ZFRs; however, as in other rats with dietary obesity, no ligament ossifi cation changes were seen at the spinal ligament sites. 

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