Study of Heart and Renal Protection (SHARP).

  title={Study of Heart and Renal Protection (SHARP).},
  author={Colin N. Baigent and Martin Landry},
  journal={Kidney international. Supplement},
Among patients with preexisting coronary heart disease, large-scale randomized trials have demonstrated that lowering low-density lipoprotein (LDL)-cholesterol concentration by about 1 mmol/L for 4-5 years reduces the risk of coronary events and strokes by about 25%. Patients with established chronic kidney disease (CKD) are at high risk of vascular disease, so the benefits of cholesterol-lowering therapy might be expected to be substantial in this population. Patients with CKD have generally… CONTINUE READING