Study of Crystal Formation and Nitric Oxide (NO) Release Mechanism from S-Nitroso-N-acetylpenicillamine (SNAP)-Doped CarboSil Polymer Composites for Potential Antimicrobial Applications.

@article{Wo2017StudyOC,
  title={Study of Crystal Formation and Nitric Oxide (NO) Release Mechanism from S-Nitroso-N-acetylpenicillamine (SNAP)-Doped CarboSil Polymer Composites for Potential Antimicrobial Applications.},
  author={Yaqi Wo and Zi An Li and Alessandro Colletta and Jian-Feng Wu and Chuanwu Xi and Adam J Matzger and Elizabeth J. Brisbois and Robert H. Bartlett and Mark E Meyerhoff},
  journal={Composites. Part B, Engineering},
  year={2017},
  volume={121},
  pages={
          23-33
        }
}
Stable and long-term nitric oxide (NO) releasing polymeric materials have many potential biomedical applications. Herein, we report the real-time observation of the crystallization process of the NO donor, S-nitroso-N-acetylpenicillamine (SNAP), within a thermoplastic silicone-polycarbonate-urethane biomedical polymer, CarboSil 20 80A. It is demonstrated that the NO release rate from this composite material is directly correlated with the surface area that the CarboSil polymer film is exposed… CONTINUE READING
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