Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells.

@article{Cheng2005StudyFA,
  title={Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells.},
  author={J. J. A. Cheng and Nai-Kuei Huang and Tun-tschu Chang and Danny L Wang and Mei-Kuang Lu},
  journal={Life sciences},
  year={2005},
  volume={76 26},
  pages={
          3029-42
        }
}
The main purposes of this study were to investigate the regulation of polysaccharides isolated from A. cinnamomea on vascular endothelial growth factor (VEGF)-induced cyclin D1 expression and down stream signaling pathway that may correlate with their anti-angiogenc effects in endothelial cells (ECs). Crude and fractionated polysaccharides (Fra-1 to Fra-4) of A. cinnamomea showed slightly toxicity to ECs as compared with their inhibition concentration on angiogenic-related gene expression. The… CONTINUE READING
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