Study Advancement of MicroRNA and Its Target Gene Polymorphism and Colorectal Tumorigenesis

@inproceedings{Lingju2014StudyAO,
  title={Study Advancement of MicroRNA and Its Target Gene Polymorphism and Colorectal Tumorigenesis},
  author={Zhu Lingju},
  year={2014}
}
Colorectal cancer(CRC) is one of the most common cancers worldwide. Recent years, some studies show that miRNAs contribute to the development of CRC. Single Nucleotide Polymorphisms(SNP) of miRNAs alos may be the risk of CRC due to change their structure and function.. In this review, alterations of miRNAs in CRC and the relation between SNPs in miRNAs and target sites and CRC risk would be showed. Furthermore, the SNPs in miRNAs may be useful in diagnose and prognosis of CRC and so on.