Studies with human leukocyte lysosomes. Evidence for antilysosome antibodies in lupus erythematosus and for the presence of lysosomal antigen in inflammatory diseases.

@article{Bell1975StudiesWH,
  title={Studies with human leukocyte lysosomes. Evidence for antilysosome antibodies in lupus erythematosus and for the presence of lysosomal antigen in inflammatory diseases.},
  author={David A. Bell and P A Thiem and John H. Vaughan and John P. Leddy},
  journal={The Journal of clinical investigation},
  year={1975},
  volume={55 2},
  pages={256-68}
}
Human lysosomes were isolated from normal peripheral blood leukoyctes and characterized by electron microscopy, enzyme analysis, and assays for DNA and RNA. Stored sera from 37 unselected patients with systemic lupus erythematosus (SLE), including active and inactive, treated and untreated cases, were tested in complement fixation (CF) reactions with these… CONTINUE READING