Studies with cultured human epidermal keratinocytes: Potential relevance to corneal wound healing

Abstract

Human epidermal cells (keratinocytes) can be grown in culture under conditions in which they form stratified sheets with the same basic characteristics as the tissue from which they are derived. l Proliferation takes place in the basal lay�r and cells which have left that layer undergo terminal differentiation as they move through the supra­ basal layers; eventually, dead cornified squames detach into the culture medium. The availability of human kera­ tinocyte cultures has allowed us to investigate the factors that regulate keratinocyte growth, differentiation and stratification. Recent evidence points to a role of adhesive receptors of

DOI: 10.1038/eye.1994.40

Cite this paper

@article{Watt1994StudiesWC, title={Studies with cultured human epidermal keratinocytes: Potential relevance to corneal wound healing}, author={Fiona M Watt}, journal={Eye}, year={1994}, volume={8}, pages={161-162} }