Studies on translocation of immunoglobulins across intestinal epithelium

  title={Studies on translocation of immunoglobulins across intestinal epithelium},
  author={Dr. Bruce K. Borthistle and Kiyoko Isobe and William R. Brown},
  journal={The American Journal of Digestive Diseases},
We tested the hypothesis that the secretion of IgA into intestinal fluids is modulated by increases in epithelial cell cyclic AMP. Cholera enterotoxin instilled into intestinal loops of rabbits did not induce IgA secretion, even though an appropriate fluid response was obtained. The findings, therefore, do not support the hypothesis. 
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