Studies on the role of ribosomes in the regulation of protein synthesis in hypophysectomized and thyroidectomized rats.

Abstract

Polyribosomes were obtained from the livers of hypophysectomized and control rats. Although sucrose gradient analysis disclosed that polyribosome profiles of the livers of hypophysectomized animals were identical with those of livers derived from intact controls, the rate of amino acid incorporation into hepatic protein in vitro was lower in the… (More)

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