Studies on the regenerative recovery of long-term denervated muscle in rats.

@article{Carlson1996StudiesOT,
  title={Studies on the regenerative recovery of long-term denervated muscle in rats.},
  author={Bruce Martin Carlson and L Billington and J. A. Faulkner},
  journal={Restorative neurology and neuroscience},
  year={1996},
  volume={10 2},
  pages={77-84}
}
Denervated extensor digitorum longus (EDL) muscles in rats rapidly lose mass and contractile force. After two months of denervation, mass and maximum tetanic force have fallen to 31% and 2% of the values of contralateral control muscles. Our purpose was to determine if grafting a long-term denervated muscle into an innervated site provides an effective means of restoring its structure and function. EDL muscles that had been denervated for periods of 2-12 months were freely grafted into… CONTINUE READING
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