Studies on the production of branched-chain alcohols in engineered Ralstonia eutropha

@article{Lu2012StudiesOT,
  title={Studies on the production of branched-chain alcohols in engineered Ralstonia eutropha},
  author={Jingnan Lu and Christopher J. Brigham and Cl{\'a}udia Santos Gai and Anthony J. Sinskey},
  journal={Applied Microbiology and Biotechnology},
  year={2012},
  volume={96},
  pages={283-297}
}
Wild-type Ralstonia eutropha H16 produces polyhydroxybutyrate (PHB) as an intracellular carbon storage material during nutrient stress in the presence of excess carbon. In this study, the excess carbon was redirected in engineered strains from PHB storage to the production of isobutanol and 3-methyl-1-butanol (branched-chain higher alcohols). These branched-chain higher alcohols can directly substitute for fossil-based fuels and be employed within the current infrastructure. Various mutant… Expand
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