Studies on the pre-alpha-lipoprotein in patients with familial lecithin: cholesterol acyltransferase deficiency.

@article{Wille1977StudiesOT,
  title={Studies on the pre-alpha-lipoprotein in patients with familial lecithin: cholesterol acyltransferase deficiency.},
  author={L. E. Wille and Harald Torsvik and Egil Gjone},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1977},
  volume={77 3},
  pages={423-9}
}
The present study shows that regular alpha1- and pre-alpha-lipoproteins cannot be detected in serum of patients with familial lecithin: cholesterol acyltransferase (LCAT) deficiency. After electrophoresis on agarose gel only one single band of albumin mobility was observed in the alpha1-pre-alpha-region. In contrast to sera of normal subjects neither the anodic front nor the cathodic part of this region revealed any lipoprotein bands in the patients studied. The lack of the cathodic part might… CONTINUE READING