Studies on the position of six amino acid substitutions in the tryptophan synthetase A protein.


Previous studies with the A protein of the tryptophan synthetase of Escherichia coli have shown that two closely linked genetic alterations are associated with amino acid substitutions in the same peptide, TP3C1, of the A protein (1, 2). One of these substitutions, in the A protein of mutant A-23, involved the replacement of a glycine residue of the wild… (More)

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