Studies on the origin of the alpha-haemolysin produced by Escherichia coli.

@article{Jorgensen1976StudiesOT,
  title={Studies on the origin of the alpha-haemolysin produced by Escherichia coli.},
  author={Sam Jorgensen and E C Short and Harold J. Kurtz and H K Mussen and Guanzheng Wu},
  journal={Journal of medical microbiology},
  year={1976},
  volume={9 2},
  pages={173-89}
}
Synthesis of alpha-haemolysin by Escherichia coli was proportional to the amount of meat-broth factor present in the medium and not to bacterial growth. The meat-broth component required for the synthesis of haemolysin was found to have several physical and chemical properties in common with alpha-haemolysin itself. Both molecules are trypsin-sensitive, acidic substances with similar elution volumes when subjected to gel-filtration chromatography with Sepharose 6B. Isotopic labelling… CONTINUE READING