• Medicine
  • Published in Endokrinologie 1978

Studies on the metabolism of steroid hormones in a virilizing adrenal cortex adenoma.

@article{Lisboa1978StudiesOT,
  title={Studies on the metabolism of steroid hormones in a virilizing adrenal cortex adenoma.},
  author={Belis{\'a}rio P. Lisboa and Manfred Strassner and L. Nocke-Finck and Heinz Gunter Breuer and Jakob M. Bayer},
  journal={Endokrinologie},
  year={1978},
  volume={72 3},
  pages={
          311-26
        }
}
Slices of an adreno-cortical adenoma which had been obtained at operation from an 11-year-old girl with clinical signs of virilism were incubated with each of the following steroids: [1,2-3H]progesterone, [4-14C]pregnenolone, [1,2-3H]testosterone, [4-14C]androstenedione and [7-3H]dehydroepiandrosterone, respectively. Isolation and identification of the free radioactive metabolites were achieved by gel column chromatography on Sephadex LH-20, thin-layer chromatography, radio gas chromatography… CONTINUE READING