Studies on the mechanism of Salmonella typhimurium enterotoxin-induced diarrhoea.

@article{Khurana1991StudiesOT,
  title={Studies on the mechanism of Salmonella typhimurium enterotoxin-induced diarrhoea.},
  author={Sumeeta Khurana and Nirmal Kumar Ganguly and Madhu Khullar and Debadatta Panigrahi and Brij N S Walia},
  journal={Biochimica et biophysica acta},
  year={1991},
  volume={1097 3},
  pages={171-6}
}
The unidirectional fluxes of Na+ and Cl- were studied in Salmonella typhimurium enterotoxin-treated rats. There was net secretion of Na+ and Cl- in toxin-treated animals, while in control animals there was net absorption of these ions. In the presence of the Ca(2+)-ionophore, there was net secretion of Na+ and Cl- in the control group, while the ionophore enhanced the secretion of these ions in experimental animals. The calcium channel blocker, verapamil, decreased the secretion induced by… CONTINUE READING

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