Studies on the mechanism by which phytohemagglutinin rapidly stimulates phospholipid metabolism of human lymphocytes

@inproceedings{Fisher1971StudiesOT,
  title={Studies on the mechanism by which phytohemagglutinin rapidly stimulates phospholipid metabolism of human lymphocytes},
  author={Daniel B. Fisher and Gerald C. Mueller},
  year={1971}
}
Abstract The growth initiator phytohemagglutinin rapidly accelerates 32Pi incorporation into lymphocyte phosphatidylinositol. This study shows that phytohemagglutinin rapidly accelerates myo-[2-3H]inositol incorporation (1800%) but only slightly increases [2-3H]glycerol and inhibits [1-14C]oleic acid incorporation into phosphatidylinositol. A convenient method for isolating the lymphocyte plasma membrane and nuclear fractions is described. 3 min exposure of lymphocytes to phytohemagglutinin… CONTINUE READING

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