Studies on the interaction between mitochondria and the cytoskeleton.

  title={Studies on the interaction between mitochondria and the cytoskeleton.},
  author={Martin Lind{\'e}n and B. Dean Nelson and Dragutin Lon{\vc}ar and Jean François Leterrier},
  journal={Journal of bioenergetics and biomembranes},
  volume={21 4},
Mitochondrial movements and morphology are regulated through interactions with the cytoskeletal system, in particular the microtubules. An interaction between the microtubule-associated proteins (MAPs) and the outer surface of rat brain mitochondria has been demonstrated in vitro and in situ. One of the MAPs, MAP2, binds to specific high-affinity sites on the outer membrane. Upon binding, MAP2 is released from microtubules, and it induces a physical alteration in the outer membrane which is… CONTINUE READING

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