Studies on the immunogenicity of an Escherichia coli extract after oral application in mice.

@article{Baier1997StudiesOT,
  title={Studies on the immunogenicity of an Escherichia coli extract after oral application in mice.},
  author={Wiltrud Baier and E A Sedelmeier and Wolfgang Bessler},
  journal={Arzneimittel-Forschung},
  year={1997},
  volume={47 8},
  pages={980-5}
}
A bacterial extract (IBEC, OM-89, Uro-Vaxom), consisting of immunostimulating components derived from 18 Escherichia coli (E. coli) bacterial strains, is used for the treatment of recurrent infections of the urinary tract. Previously it was demonstrated that IBEC constitutes an active immunogen after parenteral administration to mice. Here, the immunogenic properties of IBEC after oral administration to mice are demonstrated. It was shown that, after repeated oral administrations of the extract… CONTINUE READING

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