Studies on the identity of the optic nerve transmitter.

@article{Tebcis1973StudiesOT,
  title={Studies on the identity of the optic nerve transmitter.},
  author={A. K. Tebēcis},
  journal={Brain research},
  year={1973},
  volume={63},
  pages={
          31-42
        }
}
  • A. Tebēcis
  • Published 7 December 1973
  • Chemistry, Medicine
  • Brain research
Abstract l - and d -glutamate, l - and d -aspartate, l - and d -cysteate, l -cysteine sulphinate, and to a considerably lesser extent (if at all), N-acetyl- l -aspartate, excite lateral geniculo-cortical relay cells. 5-Hydroxytryptamine (5-HT) blocks the spontaneous and synaptic firing of lateral geniculate nucleus (LGN) neurones evoked by photic stimulation in concentrations that have little or no effect on the actions of these excitatory amino acids. If this effect of 5-HT reflects… 
Amino acids and N-acetyl-aspartyl-glutamate as neurotransmitter candidates in the monkey retinogeniculate pathways
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Several types of Ca2+ channels mediate glutamatergic synaptic responses to activation of single Thy-1-immunolabeled rat retinal ganglion neurons
  • H. Taschenberger, R. Grantyn
  • Biology, Medicine
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1995
TLDR
The experiments indicate that (1) the transmitter released by RGNs is glutamate and (2) the major part of synaptic glutamate release is governed by a novel toxin-resistant Ca2+ channel.
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