Studies on the glycoprotein associated with Rh (rhesus) blood group antigen expression in the human red blood cell membrane.

@article{Ridgwell1994StudiesOT,
  title={Studies on the glycoprotein associated with Rh (rhesus) blood group antigen expression in the human red blood cell membrane.},
  author={Kay Ridgwell and S A Eyers and William J. Mawby and David J Anstee and Michael J. A. Tanner},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 9},
  pages={6410-6}
}
The blood group Rh antigens are associated with non-glycosylated 30-kDa erythrocyte membrane proteins (the Rh30 polypeptides) and the Rh glycoprotein. We used antipeptide antibodies to study the Rh glycoprotein in human erythrocyte membranes. The Rh glycoprotein was present in Rhnull U+ve cells. However, the N-glycan chain of the Rh glycoprotein in Rhnull U+ve cells was smaller than in normal cells. In contrast, the N-glycan chain of the Rh glycoprotein was larger than normal in glycophorin B… CONTINUE READING