Studies on the formation of phthalanilide-deoxyribonucleic acid complexes and their relationship to chemotherapeutic activity.

Abstract

nucleus are thought to be critical to the function of DNA as a coding template for messenger RNA synthesis (1, 3, 13, 30). Oligoamines and diamines have been reported to interact with DNA to raise the temperature at which the helix †" 4 coil transition occurs (10, 16†" 19, 31). Diamines, such as cadaverine, also protect against the dark inactiva tion of… (More)

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