Studies on the anti-oedematogenic properties of a fraction rich in lonchocarpin and derricin isolated from Lonchocarpus sericeus

@article{Fontenele2009StudiesOT,
  title={Studies on the anti-oedematogenic properties of a fraction rich in lonchocarpin and derricin isolated from Lonchocarpus sericeus},
  author={J. Fontenele and L. Leal and F. F{\'e}lix and E. Silveira and G. Viana},
  journal={Natural Product Research},
  year={2009},
  volume={23},
  pages={1677 - 1688}
}
The acute anti-inflammatory properties of a fraction rich in the chalcones lonchocarpin and derricin, from the roots of Lonchocarpus sericeus (HFLS), were studied for the first time, using a paw oedema model induced in rats by various stimuli. Results showed that HFLS (100 and 200 mg kg−1, i.p.) was ineffective in inhibiting dextran-induced paw oedema. The HFLS (200 mg kg−1, p.o. or i.p.) also failed to inhibit the bradykinin-induced oedema. In the yeast-elicited oedema, the HFLS (200 mg kg−1… Expand

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