Studies on the age-dependent nature of the response to LHRH given via different routes.


The effect of synthetic LHRH on circulating levels of LH and FSH in three groups of male rats, prepubertal, pubertal and adult, was compared after intravenous, intraperitoneal and subcutaneous administration. In two further series of experiments, infusion of LHRH over 120 min or two i.v. bolus injection at an interval of 60 min were carried out. Blood was… (More)