Studies on the abnormal excretion of pyrimidine nucleosides in the urine of Yoshida ascites sarcoma-bearing rats. Increased excretion of deoxycytidine, pseudouridine and cytidine.

@article{Shimizu1978StudiesOT,
  title={Studies on the abnormal excretion of pyrimidine nucleosides in the urine of Yoshida ascites sarcoma-bearing rats. Increased excretion of deoxycytidine, pseudouridine and cytidine.},
  author={Manabu Shimizu and Satoshi Fujimura},
  journal={Biochimica et biophysica acta},
  year={1978},
  volume={517 2},
  pages={
          277-86
        }
}
Abstract Yoshida ascites sarcoma-bearing rats excreted significantly higher quantities of deoxycytidine and pseudouridine in urine than normal rats, with a peak 5 days after transplantation of the tumor cells, and excretion of cytidine peaking 3 or 4 days later. The contribution by the injected [14C]orotic acid to labeling of urinary deoxycytidine was 32 and 3 times higher than that by [14C]uridine or [14C]cytidine, respectively. Urinary pseudouridine was also labeled 5–6 times greater by [14C… CONTINUE READING