Studies on the abnormal excretion of pyrimidine nucleosides in the urine of Yoshida ascites sarcoma-bearing rats. Increased excretion of deoxycytidine, pseudouridine and cytidine.

Manabu Shimizu; Satoshi Fujimura

Studies on the abnormal excretion of pyrimidine nucleosides in the urine of Yoshida ascites sarcoma-bearing rats. Increased excretion of deoxycytidine, pseudouridine and cytidine.

@article{Shimizu1978StudiesOT,
  title={Studies on the abnormal excretion of pyrimidine nucleosides in the urine of Yoshida ascites sarcoma-bearing rats. Increased excretion of deoxycytidine, pseudouridine and cytidine.},
  author={Manabu Shimizu and Satoshi Fujimura},
  journal={Biochimica et biophysica acta},
  year={1978},
  volume={517 2},
  pages={
          277-86
        }
}

Manabu Shimizu, Satoshi Fujimura
Published in Biochimica et biophysica acta 1978
DOI:10.1016/0005-2787(78)90194-6

Abstract Yoshida ascites sarcoma-bearing rats excreted significantly higher quantities of deoxycytidine and pseudouridine in urine than normal rats, with a peak 5 days after transplantation of the tumor cells, and excretion of cytidine peaking 3 or 4 days later. The contribution by the injected [14C]orotic acid to labeling of urinary deoxycytidine was 32 and 3 times higher than that by [14C]uridine or [14C]cytidine, respectively. Urinary pseudouridine was also labeled 5–6 times greater by [14C… CONTINUE READING

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