Studies on the Sensitization of Animals with Simple Chemical Compounds. Ii

@article{Landsteiner1936StudiesOT,
  title={Studies on the Sensitization of Animals with Simple Chemical Compounds. Ii},
  author={Karl Landsteiner and John Jacobs},
  journal={The Journal of Experimental Medicine},
  year={1936},
  volume={64},
  pages={625 - 639}
}
In continuation of previous work sensitization experiments have been made with various substances such as urushiol, benzyl chlorides, and acyl chlorides. In the case of a series of substituted benzenes (Cl, NO(2)) a connection between sensitizing capacity and lability of the Cl or NO(2) groups has been shown, indicating the formation of conjugated antigens in the animal. This led to the study of benzyl and acyl chlorides which, actually, were found to have sensitizing capacity. Most informative… CONTINUE READING

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