Studies on the Formation of Transfer Ribonucleic Acid- Ribosome Complexes, Xi. Antibiotic Effects on Phenylalanyl-oligonucleotide Binding to Ribosomes by Sidney Pestka*


-The effect of antibiotics on the binding of phenylalanyl-oligonucleotide to ribosomes has been examined. The results show that many classes of antibiotics can interfere with binding of the aminoacyl-oligonucleotide terminus of tRNA to ribosomes: chloramphenicol, sparsomycin, D-WIN-5094, vernamycin A, PA114A, streptogramin, amicetin, gougerotin, tylosin… (More)


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