Studies on the Escherichia coli glucose-specific permease, PtsG, with a point mutation in its N-terminal amphipathic leader sequence.

Abstract

Previous work has resulted in the isolation of several mutant glucose permeases (II(Glc) or PtsG) of the Escherichia coli phosphotransferase system (PTS) with altered N-terminal amphipathic leader sequences. The mutations were reported to (1). broaden permease substrate specificity, (2). promote facilitated diffusion of some sugars and (3). increase ptsG… (More)

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