Studies on reconstituted myoglobins and hemoglobins. II. Role of the heme side chains in the oxygenation of hemoglobin.

@article{Kawabe1982StudiesOR,
  title={Studies on reconstituted myoglobins and hemoglobins. II. Role of the heme side chains in the oxygenation of hemoglobin.},
  author={Koichi Kawabe and Katsumi Imaizumi and Z I Yoshida and Kiyohiro Imai and I Tyuma},
  journal={Journal of biochemistry},
  year={1982},
  volume={92 6},
  pages={1703-12}
}
To clarify the functional role of the 2- and 4-side chains of heme in hemoglobin we prepared several hemins carrying nonnatural side chains at positions 2 and 4, reconstituted human adult hemoglobins with them, and investigated their optical and oxygen binding properties. The absorption maxima for all these reconstituted hemoglobins, no matter whether they… CONTINUE READING