Studies on porphyrin biosynthesis in lead-intoxicated rabbits.

  title={Studies on porphyrin biosynthesis in lead-intoxicated rabbits.},
  author={Leonor Carmen San Mart{\'i}n de Viale and R W de Calmanovici and Mar{\'i}a del Carmen R{\'i}os de Molina and M Grinstein},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  volume={69 3},
The present report deals with studies on porphyrins and porphyrinogen carboxy-lyase of red cells and urinary porphyrins from lead-intoxicated rabbits. It was shown that the free erythrocyte porphyrins are mixture of protoporphyrin 9, the main component, and minor proportions of Coproporphyrin, Uroporphyrin III and Phyriaporphyrin. Analysis of the urinary porphyrins deomonstrates the presence of Coproporphyrins III as the major component, together with 15-20% of other porphyrins: 10-14% 5-COOH… CONTINUE READING


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