Studies on persistent circulating immunoreactive glucagon (IRG) and immunoreactive insulin (IRI) found in eviscerated rats with a functional liver

@article{Smith1978StudiesOP,
  title={Studies on persistent circulating immunoreactive glucagon (IRG) and immunoreactive insulin (IRI) found in eviscerated rats with a functional liver},
  author={Sheryl Sue Smith and Sam J. Bhathena and Dominic J. Nompleggi and Juan Carlos Penhos and Lillian Recant},
  journal={Diabetologia},
  year={1978},
  volume={14},
  pages={177-184}
}
SummaryEviscerated rats (animals without gastrointestinal tract or pancreas, but with intact liver and kidneys) are diabetic with blood glucose levels of 287 ± 10 mg% (n = 35) 24 h after surgery. Immunoreactive insulin (IRI) and immunoreactive glucagon (IRG) persisted in these animals at plasma levels of 36 ± 4 μU/ml and 0.29 ± 0.02 ng/ml, respectively. Twenty-four h fasted sham-operated controls, on the other hand, had blood glucose levels of 101 ± 3mg%, plasma IRI levels of 62 ± 8 μU/ml and… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-3 OF 3 CITATIONS

Immunoreactive Insulin in Rat Salivary Glands and Its Dependence on Age and Serum Insulin Levels

Effects of Diabetes on Development of Small Intestinal Enzymes of Infant Rats

References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Immunocytochemical evidence for glucagon-containing cells in the human stomach.

Mobilization and distribution of subcutaneously injected 3 Hinsulin : effects of exercise

  • I. Valverde, M. L. Villaneuva, I. Lozano, J. Marco
  • Diabetes
  • 1977

Blood glucagon alterations in response to arginine and somatostatin ( SRIF ) in the pancreateetomized and streptozotocin ( STZ ) diabetic monkey

  • G. Hoganson, G. Huss, G. Hoversten, R. Hastings
  • 1976