Studies on new antiplatelet agents, WS-30581 A and B.

  title={Studies on new antiplatelet agents, WS-30581 A and B.},
  author={Kaoru Umehara and Kenichi Yoshida and Masaki Okamoto and Mika Iwami and Hiromichi Tanaka and Masanobu Kohsaka and Hiroyuki Imanaka},
  journal={The Journal of antibiotics},
  volume={37 10},
WS-30581 A and B are antiplatelet agents produced by a strain of Streptoverticillium waksmanii. The compounds were purified by solvent extraction and column chromatography, and identified as new pimprinine analogs on the basis of their physico-chemical properties. The producing organism produced pimprinine along with these compounds. Pimprinine and the two new analogs have potent inhibitory effects on platelet aggregation. 

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