• Corpus ID: 189757093

Studies on natural C-glycoside, mayamycin and hydroxystilbenoids

  title={Studies on natural C-glycoside, mayamycin and hydroxystilbenoids},
  author={Prithiba Mitra},
A general and convergent route has been developed for the regio- and stereoselective construction of the C-5 glycosyl angucycline framework of mayamycin. The C-glycosylation of 2-naphthol, dearomatization and Hauser annulation has been the key steps. The total synthesis of the natural product by applying this methodology was restricted by the steric perturbation of the methyl substituent in the C-glycosylation step. The peri effects in the C-glycosylation of the substituted 2-naphthols were…