Studies on marine microorganisms. V. A new antibiotic, aplasmomycin, produced by a streptomycete isolated from shallow sea mud.

Abstract

A new antibiotic, aplasmomycin, which inhibits growth of Gram-positive bacteria including myobacteria in vitro, and plasmodia in vivo was obtained from a strain of Streptomyces griseus isolated from shallow sea sediment in Sagami Bay. The antibiotic forms colorless needle-like crystals and has a molecular formula of C41H60O14Na. Based on its physical and chemical properties, aplasmomycin was concluded to be a new antibiotic. The antibiotic was produced in selected media devised to relate to a marine environment.

0100200'88'91'94'97'00'03'06'09'12'15
Citations per Year

616 Citations

Semantic Scholar estimates that this publication has 616 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Okami1976StudiesOM, title={Studies on marine microorganisms. V. A new antibiotic, aplasmomycin, produced by a streptomycete isolated from shallow sea mud.}, author={Yoshiro Okami and Tomoki Okazaki and Takao Kitahara and Hamao Umezawa}, journal={The Journal of antibiotics}, year={1976}, volume={29 10}, pages={1019-25} }