Studies on interactions between functional foods or dietary supplements and medicines. IV. Effects of ginkgo biloba leaf extract on the pharmacokinetics and pharmacodynamics of nifedipine in healthy volunteers.

@article{Yoshioka2004StudiesOI,
  title={Studies on interactions between functional foods or dietary supplements and medicines. IV. Effects of ginkgo biloba leaf extract on the pharmacokinetics and pharmacodynamics of nifedipine in healthy volunteers.},
  author={Mutsunobu Yoshioka and Noriaki Ohnishi and Tomokazu Koishi and Yukihisa Obata and Masato Nakagawa and Tsuyoshi Matsumoto and Kentaro Tagagi and Koji Takara and Tsuyoshi Ohkuni and Teruyoshi Yokoyama and Kazuo Kuroda},
  journal={Biological & pharmaceutical bulletin},
  year={2004},
  volume={27 12},
  pages={
          2006-9
        }
}
  • Mutsunobu Yoshioka, Noriaki Ohnishi, +8 authors Kazuo Kuroda
  • Published in
    Biological & pharmaceutical…
    2004
  • Medicine
  • The effects of Ginkgo biloba leaf extract (GBE), a widely used herbal dietary supplement in Japan, on the pharmacokinetics and pharmacodynamics of nifedipine (NFP), a calcium-channel blocker, were studied using 8 healthy volunteers. Simultaneous oral ingestion of GBE (240 mg) did not significantly affect any of the mean pharmacokinetic parameters of either NFP or dehydronifedipine, a major metabolite of NFP, after oral administration of NFP (10 mg). However, the maximal plasma NFP… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 22 CITATIONS

    Ginkgo biloba Extract for Patients with Early Diabetic Nephropathy: A Systematic Review

    VIEW 1 EXCERPT
    CITES BACKGROUND