Studies on inflammation in mice: dynamics of inflammatory response induced by extract from Escherichia coli and influence of antiinflammatory drugs.


The intraperitoneal injection of E. coli extract in the mouse resulted in a biphasic accumulation of leukocytes. The first phase of leukocyte accumulation was based on neutrophil influx in the peritoneal cavity, which occurred 1-2 days after E. coli extract administration. The second phase was based on macrophage influx, which occurred 12 days after E. coli… (More)


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