Studies on factor VIII activation potential in hemophilia A-plasma and its significance for the comprehension of hemophilia

@article{Mingers1976StudiesOF,
  title={Studies on factor VIII activation potential in hemophilia A-plasma and its significance for the comprehension of hemophilia},
  author={A. -M. Mingers},
  journal={European Journal of Pediatrics},
  year={1976},
  volume={123},
  pages={187-198}
}
In a factor VIII exchange test experiment higher factor VIII activities are measurable than would be expected from the single activities of the used plasmas. The same goes for the use of plasmas from carriers of hemophilia A, but not for plasmas from patients with v. W.J.S. (von-Willebrand Jürgens syndrome). In plasmas from hemophilic adults activation obviously proceeds at a slower rate than in plasmas from hemophilic children. The experimental results lead to the hypothesis that factor VIII… CONTINUE READING